Cognitive changes in (natural and experimental) hyperthyroidism.
Cognitive domain
Hyperthyroidism
Natural
Experimental
T3(b)
T4(d)
T4(e)
100 g/day
300 g/day
500 g/day
for 3 days
for 21 days
for 45 days
Attention
Impaired(a)
No change
Not reported
No change
Memory
Impaired(a)
No change
Not reported
No change
Visuospatial abilities
Impaired(a)
No change
Impaired
No change
Motor speed
Impaired(a),(b)
Not reported
Not reported
Not reported
No change(c)
Verbal fluency
No change(b)
Accelerated
Not reported
No change
(a)Whybrow et al. [49],
MacCrimmon et al. [51], Alvarez et al. [52],
Trzepacz et al. [53], Toft [54];
(b)Kathman et al. [56];
(c)Zeitlhofer et al. [55];
(d)Münte et al. [58];
(e)Baethge et al. [59].
