Deficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in Mice

Figure 6

Age-related holding strength of PARP-1^−/− and PARP-1^+/+ mice. The hung on the string duration of PARP-1^−/− and PARP-1^+/+ mice was tested at the ages indicated by their holding a string, and the duration (in second) of holding a string was recorded. Student’s t test was performed to analyze the statistical significance of the results.