Current Gerontology and Geriatrics Research / 2009 / Article / Tab 2

Clinical Study

Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C

Table 2

Hazard ratios for major cardiovascular event defined as hospitalization or death caused by myocardial infarction, stroke, or ruptured aortic aneurysm or all-cause mortality according to serum levels of cholesterol and its subfractions.

Major cardiovascular eventAll-cause mortality
Men ( )Women ( )Men ( )Women ( )
HR (95% CI)*PHR (95% CI)*PHR (95% CI)*PHR (95% CI)*P

Total cholesterol1.01 (0.96–1.07).681.00 (0.93–1.07).940.97 (0.92–1.02).290.95 (0.90–1.00).065
LDL-C1.02 (0.96–1.09).441.02 (0.93–1.11).720.97 (0.92–1.03).340.99 (0.92–1.06).73
Non-HDL-C1.03 (0.98–1.09).251.01 (0.95–1.08).770.99 (0.95–1.04).820.97 (0.93–1.02).20
Total cholesterol/HDL-C ratio1.19 (1.00–1.40).0461.13 (0.89–1.45).321.10 (0.95–1.29).201.07 (0.90–1.29).44
HDL-C0.76 (0.61–0.94).0110.93 (0.78–1.10).400.78 (0.65–0.94).0090.93 (0.82–1.07).32
HDL-C adjusted0.71 (0.55–0.90).0061.01 (0.83–1.23).940.76 (0.62–0.94).0110.93 (0.80–1.07).31

*Hazard ratios and 95% confidence intervals for every unit increase of the total cholesterol/HDL-C ratio and for every 10 mg/dL increase of the other independent variables.
Adjusted for smoking, non-HDL-C, triglycerides, diabetes, hypertension, previous stroke, and previous myocardial infarction.

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