Brain Tumor Diagnostics and Therapeutics with Superparamagnetic Ferrite Nanoparticles

Table 1

Physical characterization of Fe_xCo_1−xFe₂O₄ (where ) for bare and coated (chitosan, PEG) nanoparticles using different coprecipitating agents (NH₄OH, NaOH) for chemical synthesis. See Figure 4 for other details [10].

	Method used	Grain size (nm)	Lattice (Å)	Blocking temperature (°C)	Hydrodynamic diameter (nm)		Maximum magnetization (emu/g)			Coercivity (Oe)			Relaxivity (mM^−1s^−1)
					Chitosan	PEG	Bare	Chitosan	PEG	Bare	Chitosan	PEG	Chitosan	PEG
0.8	NH4OH	4.0 (±0.6)	8.48 (±0.06)		97.5	158.3	59.3	37.2	26.0	3.5	2.08	1.4	528 (±26)	314 (±25)
0.6	NH4OH	4.5 (±0.1)	8.52 (±0.26)	25	135.5	154.5	55.3	28.0	20	20	7.5	8.6	509 (±45)	441 (±12)
0.4	NH4OH	2.8 (±0.1)	8.45 (±0.20)	65	140.6	159.1	43.6	25.2	16.9	157	4.2	4.8	326 (±37)	310 (±5)
0.2	NH4OH	—	—	100	110.0	155.5	32.3	—	—	506	—	—	—	—
0.2	NaOH	4.9 (±0.1)	8.43 (±0.05)	—	—	—	73.1	54.5	46.6	673	11.5	7.8	769 (±92)	377 (±14)