Three-Year Successful Cinacalcet Treatment of Secondary Hyperparathyroidism in a Patient with X-Linked Dominant Hypophosphatemic Rickets: A Case Report

Figure 1

Plasma levels of PTH, ionized-calcium (Figure 1(a)), and phosphate (Figure 1(b)) three years before initiation of cinacalcet treatment and during the three years of cinacalcet treatment. Start of cinacalcet treatment, as indicated by the vertical line, was March 2010. Top bars show dosage of medical treatment. CaD; calcium carbonate 250 mg with 30 μg/d (1200 IU) of cholecalciferol. Reference intervals of plasma PTH (1.6–6.9 pmol/L) are indicated by the lower grey area and plasma Ca²⁺ (1.18–1.32 mmol/L) by the upper grey area. Measurements of ionized calcium (Ca²⁺) were not available prior to May 2008 (Figure 1(a)). The reference interval of plasma phosphate was 0.76–1.41 mmol/L, as indicated by the grey area (Figure 1(b)).