Immunotherapy in Metastatic Mucosal Melanoma with Disseminated Intravascular Coagulation: A Case of Success

Figure 1

Microscopically, a solid tumor infiltrates the submucosa ((a); H&E, 40x), displaying areas of geographic necrosis ((b); H&E, 200x). On higher magnification ((c); H&E, 400x), cherry-red nucleoli are conspicuous and numerous mitosis and apoptosis figures can be recognized. Neoplastic cells were positive for HMB-45 ((d); 400x), SOX-10 ((e); 400x), and Melan-A ((f); 400x) immunostaining.