Case Reports in Obstetrics and Gynecology / 2013 / Article / Tab 1

Case Report

An Unexpected Complete Remission of Advanced Intestinal-Type Vulvar Adenocarcinoma after Neoadjuvant Chemotherapy: A Case Report and a Literature Review

Table 1

The literature reported vulvar intestinal adenocarcinoma cases.

Author, yearPTS ageSurgical treatmentAdjuvant treatmentImmunohistochemical patternPFS (months)

Tiltman and Knutzen, 1978 [5]50Modified RV + GDNRNot performed12
Kennedy and Majmudar, 1993 [3]Case  1: 54 years
Case  2: 63 years
RV + bilateral GD
Wide LE
NR
NR
CK+
CEA−
120
48
Willen et al., 1999 [6]57Wide LENRCK17+
Broad CK+
Polyclonal CEA+−
Chromogranin A+−
26
Nasir et al., 2001 [4]43EV + bilateral GDNRCEA+
p53+
Broad CK+
Ras10+−
ER−
PR−
Bcl2−
c-erB2−
18
Rodriguez et al., 2001 [7]69Wide LENRCK7+
CK20+−
OC125 apical
CEA apical
OC19.9 apical
36
Liu et al., 2003 [9]49LE + bilateral GDNRNot performed24
Dubè et al., 2004 [8]58Radical EV + ipsilateral GDNRCK20+−
CK7+
ER−
PR−
16
Ghamande et al., 1995 [2]67RV + bilateral GDNRCEA+17
Cormio et al., 2012 [10]Case  1: 58 years
Case  2: 42 years
EV + GD
RV + GD
Chemotherapy
NR
CK7+
CK 20+−
54
39
Karkouche et al., 2012 [11]31LENRCK 20+
CK 7−
15
Our case57NACT + LE + ipsilateral GRCK 20+
CEA+
P16+
CDX2+ focal
Ca125+−
ER−
CK 7−
Vimentin−
17

LE: local excision, E: emivulvectomy, RV: radical vulvectomy, GD: groin dissection, NACT: neoadjuvant chemotherapy, NR: not reported.

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