Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane)

Figure 1

Color fundus photography showed cystoid macular edema (CME) in both eyes (a, b). Fluorescein angiography (FA) showed bilateral CME with minimal leakage during the late phase, before sub-Tenon injections of triamcinolone acetonide (STTA) (c, d). Optical coherence tomography (OCT) revealed cystic accumulation of fluid in the outer retina, particularly in the outer plexiform layer, before STTA (e, f). OCT showed slightly decreased CME in the right eye (g) and almost no change in the left eye (h) 1 month after STTA. However, the height of CME in each eye (i, j) decreased 2 months after cessation of nanoparticle albumin-bound- (nab-) paclitaxel. Complete resolution of CME in the right eye occurred 5 months after cessation of nab-paclitaxel (k), which was sustained at 6 months (m). CME in the left eye was markedly reduced at 5 months after nab-paclitaxel cessation (l) and complete resolution occurred 6 months after cessation (n).

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