A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings
Figure 1
Cat; testis; Leydig cell tumour. (a) Neoplastic polyhedral Leydig cells with a large, eosinophilic, and vacuolated cytoplasm and a small and dark nuclei. These cells are arranged in solid sheets surrounded by a fine connective stroma in which a vascular structure can be observed. Hematoxylin and Eosin stain, 40. (b) Diffuse cytoplasmic immunoreactivity of neoplastic cells to vimentin. Biotin-streptavidin-peroxidase method and hematoxylin counterstain. 40. (c) Weak immunolabeling of tumour cells to calretinin antibody with some foci of strong intensity. Biotin-streptavidin-peroxidase method and hematoxylin counterstain. 40. (d) Diffuse immunolabeling of neoplastic cells to melan-A antibody. Biotin-streptavidin-peroxidase method and hematoxylin counterstain. 40. Inserts: immunolabeling in normal testicular tissue to the respective markers.
