Research Article

Association of Inflammatory and Oxidative Stress Markers with Metabolic Syndrome in Asian Indians in India

Table 5

(a) Discriminant analysis results

Structure matrix
FunctionContribution (%)
1

Ln_oxLDL.74637.99
Ln_HsCRP.63927.87
Ln_Neopterin.52218.59
Ln_sPLA2.41111.53
Ln_Interleukin6.2423.99

(b) Threshold levels for the biomarkers obtained using Discriminant score

oxLDL39922.68 mU/L
hsCRP4.00 μg/ml
Neopterin7.0596 nmol/L

63.4% of cases were correctly classified using discriminant analysis.
(c) Mean levels of biomarkers for discriminant groups

VariablesDiscriminant group
(see Table 5(d))
Mean ± S.E
(retransformed mean)
𝑃 -value for group differences

hsCRP (μg/ml)1 0 . 0 6 6 ± 0 . 0 8 0 ( 0 . 9 3 6 1 ) <.0001**
2 1 . 2 4 0 ± 0 . 1 0 2 ( 3 . 4 5 5 6 )
3 0 . 3 9 3 ± 0 . 1 2 8 ( 1 . 4 8 1 4 ) <.0001**
4 1 . 2 1 9 ± 0 . 0 9 2 ( 3 . 3 8 3 8 )

OxLDL (mU/L)1 1 0 . 6 2 3 ± 0 . 0 2 2 ( 4 1 0 6 8 . 6 3 6 2 ) <.0001**
2 1 1 . 0 0 5 ± 0 . 0 2 8 ( 6 0 1 7 4 . 2 6 2 1 )
3 1 0 . 6 8 2 ± 0 . 0 3 6 ( 4 3 5 6 4 . 5 9 2 4 ) <.0001**
4 1 1 . 1 0 6 ± 0 . 0 2 6 ( 6 6 5 6 9 . 3 8 0 6 )

Neopterin (nmol/L)1 1 . 7 6 6 ± 0 . 0 3 5 ( 5 . 8 4 7 4 ) <.0001**
2 2 . 2 3 1 ± 0 . 0 4 5 ( 9 . 3 0 9 1 )
3 1 . 8 9 6 ± 0 . 0 5 6 ( 6 . 6 5 9 2 ) <.0001**
4 2 . 2 2 3 ± 0 . 0 4 0 ( 9 . 2 3 4 9 )

(d) Discriminant groups

Actual groupPredicted groupDiscriminant group

UnaffectedUnaffected1
UnaffectedAffected2
AffectedUnaffected3
AffectedAffected4