Interactions between CKD and MetS and the Development of CVD
1Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
2Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa, Tohon, Ehime 791-0295, Japan
3Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-Ku, Nagoya 466-8550, Japan
4Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Bart's and the London Queen Mary University of London, London, UK
5Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, USA
Interactions between CKD and MetS and the Development of CVD
Description
In recent years, patients with chronic kidney disease (CKD) and metabolic syndrome (MetS) appear to be increasing along with increasing cardiovascular diseases in industrial countries. In order to ameliorate cardiovascular mortality, it is essential to extend comprehensive treatments for patients with CKD and MetS. Although those disorders may be partly formed by a certain common pathological basis, there is insufficient knowledge of the underlying interplay between the pathological conditions and cardiovascular diseases. In this special issue, we are going to invite front-line researchers and authors to submit original research and review articles that explore the interaction dynamics of CKD, MetS, and cardiovascular diseases. Therefore, we are interested in articles that provide pivotal and/or novel evidence for understanding the pathophysiological relationship among the disorders and propose new strategies for treating these conditions on a clinical and molecular basis. Potential topics include, but are not limited to:
- Influence of aberrant circadian rhythm
- Pathophysiology of adipocyte-secreted factors
- Role of inflammation and oxidative stress
- Interactions of remote organs (central nervous system, digestive organs, cardiovascular system, fat tissue, etc.)
- Importance of sympathetic nervous system
- New aspects of the renin-angiotensin system
- Novel and notable biomarkers and endogenous factors
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