Positive Association between EDN1 rs5370 (Lys198Asn) Polymorphism and Large Artery Stroke in a Ukrainian Population

Table 8

Characteristics of the LAS patients stratified by EDNRA rs5335 genotype.

Parameter	Genotype			P value	PFDR
	CC ()	CG ()	GG ()
Body mass index, kg/m^2	28.7 ± 3.3	27.7 ± 3.8	27.6 ± 3.6	0.251	0.566
Systolic BP, mmHg	169.5 ± 26.9	167.3 ± 28.6	167.3 ± 32.2	0.888	0.914
Diastolic BP, mmHg	96.9 ± 12.7	96.7 ± 16.0	91.9 ± 17.3	0.261	0.566
Pulse BP, mmHg	72.6 ± 21.4	70.6 ± 21.6	75.3 ± 26.5	0.548	0.745
Mean BP, mmHg	121.2 ± 15.6	120.2 ± 18.5	117.1 ± 19.7	0.573	0.745
Total cholesterol, mmol/L	5.18 ± 1.6	5.01 ± 1.4	4.64 ± 1.4	0.257	0.566
HDL cholesterol, mmol/L	0.95 ± 0.31	1.02 ± 0.30	1.07 ± 0.27	0.179	0.566
LDL cholesterol, mmol/L	3.37 ± 1.5	3.18 ± 1.4	2.83 ± 1.3	0.235	0.566
Triglyceride, mmol/L	1.78 ± 0.8	1.66 ± 0.8	1.54 ± 0.7	0.383	0.671
Prothrombin time, s	9.81 ± 2.2	9.26 ± 1.9	9.31 ± 1.9	0.252	0.566
Thrombin time, s	16.63 ± 3.2	16.72 ± 3.6	16.96 ± 4.3	0.914	0.914
Fibrinogen, g/L	3.95 ± 1.5	4.01 ± 1.2	4.00 ± 1.3	0.878	0.912
Fasting glucose, mmol/L	6.29 ± 1.8	5.99 ± 1.3	5.89 ± 1.5	0.413	0.671

See Table 7.