High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients
Prediction of mortality by M30 serum levels. (a) Patients that died during the course of ICU treatment had significantly higher serum M30 levels on ICU admission than survivors (). (b) On Kaplan-Meier survival curve analysis, ICU patients with M30 levels above 250.8 U/L had increased ICU mortality. (c) Patients that died during the total observation period displayed a trend towards higher serum M30 levels at admission to the ICU than survivors (). (d) On Kaplan-Meier survival curve analysis, ICU patients with M30 levels above 250.8 U/L had increased overall mortality, which was apparent especially during the first 30 days after admission. The symbols “o” and “” indicate outliers.