Disease Markers / 2018 / Article / Tab 4

Research Article

High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

Table 4

Serum M30 performance as a biomarker to predict ICU or overall mortality.

ICU mortalityOverall mortality

M30 (U/L) optimal cut-off250.8250.8
Sensitivity0.610.54
Specificity0.680.70
Positive predictive value0.410.63
Negative predictive value0.830.59
Youden index0.290.21
LHR+1.921.82
LHR−0.570.65
Diagnostic odds ratio3.342.79

LHR: likelihood ratio.