Disease Markers / 2019 / Article / Tab 2

Review Article

Prognostic Significance of the Lymphocyte-to-Monocyte Ratio in Bladder Cancer Undergoing Radical Cystectomy: A Meta-Analysis of 5638 Individuals

Table 2

Pooled hazard ratios (HRs) for OS according to subgroup analyses.

SubgroupNo. of studiesNo. of patientsHR (95% CI) valueHeterogeneity

Overall85,3680.63 (0.50-0.80)<0.00165.90.005
 Asian24220.46 (0.25-0.87)0.01673.30.023
 Caucasian54,9460.80 (0.71-0.89)<0.0018.20.360
Disease stage
 Early25360.61 (0.20-1.82)0.37700.705
 Mixed64,8320.63 (0.49-0.80)<0.00175.30.001
 Surgery44,8780.81 (0.74-0.89)<0.00100.883
 Mixed44820.45 (0.27-0.73)0.00162.30.047
Cut-off for LMR
 ≥354,9300.56 (0.35-0.88)0.01176.60.002
 <334380.65 (0.41-1.04)0.07541.70.180
Analysis method
 Univariate21850.46 (0.27-0.79)0.00500.488
 Multivariate65,1830.67 (0.53-0.86)0.00165.90.005

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