Table of Contents Author Guidelines Submit a Manuscript
Dermatology Research and Practice
Volume 2010, Article ID 168248, 6 pages
http://dx.doi.org/10.1155/2010/168248
Case Report

Reflectance Confocal Microscopy as an Aid to Dermoscopy to Improve Diagnosis on Equivocal Lesions: Evaluation of Three Bluish Nodules

1Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy
2Histopathology Department, University of Modena and Reggio Emilia, Modena, Italy

Received 9 June 2010; Accepted 19 July 2010

Academic Editor: Hans Peter Soyer

Copyright © 2010 Sara Bassoli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Pehamberger, A. Steiner, and K. Wolff, “In vivo epiluminescence microscopy of pigmented skin lesions. I. Pattern analysis of pigmented skin lesions,” Journal of the American Academy of Dermatology, vol. 17, no. 4, pp. 571–583, 1987. View at Google Scholar · View at Scopus
  2. A. Steiner, H. Pehamberger, and K. Wolff, “In vivo epiluminescence microscopy of pigmented skin lesions. II. Diagnosis of small pigmented skin lesions and early detection of malignant melanoma,” Journal of the American Academy of Dermatology, vol. 17, no. 4, pp. 584–591, 1987. View at Google Scholar · View at Scopus
  3. G. Argenziano and H. P. Soyer, “Dermoscopy of pigmented skin lesions—a valuable tool for early diagnosis of melanoma,” Lancet Oncology, vol. 2, no. 7, pp. 443–449, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Kittler, H. Pehamberger, K. Wolff, and M. Binder, “Diagnostic accuracy of dermoscopy,” Lancet Oncology, vol. 3, no. 3, pp. 159–165, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. Pan, D. S. Gareau, A. Scope, M. Rajadhyaksha, N. A. Mullani, and A. A. Marghoob, “Polarized and nonpolarized dermoscopy: the explanation for the observed differences,” Archives of Dermatology, vol. 144, no. 6, pp. 828–829, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. A. R. Rhodes, “Common acquired nevomelanocytic nevi and the fourth dimension,” Archives of Dermatology, vol. 136, no. 3, pp. 400–405, 2000. View at Google Scholar · View at Scopus
  7. H. Kittler, H. Pehamberger, K. Wolff, and M. Binder, “Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi,” Journal of the American Academy of Dermatology, vol. 43, no. 3, pp. 467–476, 2000. View at Google Scholar · View at Scopus
  8. F. Nachbar, W. Stolz, T. Merkle et al., “The ABCD rule of dermatoscopy. High prospective value in the diagnosis of doubtful melanocytic skin lesions,” Journal of the American Academy of Dermatology, vol. 30, pp. 551–559, 1994. View at Google Scholar
  9. G. Argenziano, G. Fabbrocini, P. Carli, V. De Giorgi, E. Sammarco, and M. Delfino, “Epiluminescence microscopy for the diagnosis of doubtful melanocytic skin lesions: comparison of the ABCD rule of dermatoscopy and a new 7-point checklist based on pattern analysis,” Archives of Dermatology, vol. 134, no. 12, pp. 1563–1570, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. G. Argenziano, H. P. Soyer, S. Chimenti et al., “Dermoscopy of pigmented skin lesions: results of a consensus meeting via the internet,” Journal of the American Academy of Dermatology, vol. 48, no. 5, pp. 679–693, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. S. W. Menzies, C. Ingvar, K. A. Crotty, and W. H. McCarthy, “Frequency and morphologic characteristics of invasive melanomas lacking specific surface microscopic features,” Archives of Dermatology, vol. 132, no. 10, pp. 1178–1182, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Skvara, L. Teban, M. Fiebiger, M. Binder, and H. Kittler, “Limitations of dermoscopy in the recognition of melanoma,” Archives of Dermatology, vol. 141, no. 2, pp. 155–160, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Rajadhyaksha, M. Grossman, D. Esterowitz, R. H. Webb, and R. R. Anderson, “In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast,” Journal of Investigative Dermatology, vol. 104, no. 6, pp. 946–952, 1995. View at Google Scholar · View at Scopus
  14. M. Rajadhyaksha, S. González, J. M. Zavislan, R. R. Anderson, and R. H. Webb, “In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology,” Journal of Investigative Dermatology, vol. 113, no. 3, pp. 293–303, 1999. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Pellacani, C. Longo, J. Malvehy et al., “In vivo confocal microscopic and histopathologic correlations of dermoscopic features in 202 melanocytic lesions,” Archives of Dermatology, vol. 144, no. 12, pp. 1597–1608, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. G. Pellacani, M. Vinceti, S. Bassoli et al., “Reflectance confocal microscopy and features of melanocytic lesions: an internet-based study of the reproducibility of terminology,” Archives of Dermatology, vol. 145, no. 10, pp. 1137–1143, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Scope, C. Benvenuto-Andrade, A.-L. C. Agero et al., “In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images,” Journal of the American Academy of Dermatology, vol. 57, no. 4, pp. 644–658, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Guitera, G. Pellacani, C. Longo, S. Seidenari, M. Avramidis, and S. W. Menzies, “In vivo reflectance confocal microscopy enhances secondary evaluation of melanocytic lesions,” The Journal of Investigative Dermatology, vol. 129, no. 1, pp. 131–138, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. G. Pellacani, P. Guitera, C. Longo, M. Avramidis, S. Seidenari, and S. Menzies, “The impact of in vivo reflectance confocal microscopy for the diagnostic accuracy of melanoma and equivocal melanocytic lesions,” Journal of Investigative Dermatology, vol. 127, no. 12, pp. 2759–2765, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. A. A. Marghoob, L. Cowell, A. W. Kopf, and A. Scope, “Observation of chrysalis structures with polarized dermoscopy,” Archives of Dermatology, vol. 145, no. 5, p. 618, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Nori, F. Rius-Díaz, J. Cuevas et al., “Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study,” Journal of the American Academy of Dermatology, vol. 51, no. 6, pp. 923–930, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Massi, V. De Giorgi, P. Carli, and M. Santucci, “Diagnostic significance of the blue hue in dermoscopy of melanocytic lesions: a dermoscopic-pathologic study,” American Journal of Dermatopathology, vol. 23, no. 5, pp. 463–469, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. A. L. Agero, K. J. Busam, C. Benvenuto-Andrade et al., “Reflectance confocal microscopy of pigmented basal cell carcinoma,” Journal of the American Academy of Dermatology, vol. 54, no. 4, pp. 638–643, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Segura, S. Puig, C. Carrera, J. Palou, and J. Malvehy, “Dendritic cells in pigmented basal cell carcinoma: a relevant finding by reflectance-mode confocal microscopy,” Archives of Dermatology, vol. 143, no. 7, pp. 883–886, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Segura, G. Pellacani, S. Puig et al., “In vivo microscopic features of nodular melanomas: dermoscopy, confocal microscopy, and histopathologic correlates,” Archives of Dermatology, vol. 144, no. 10, pp. 1311–1320, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Bowling, G. Argenziano, A. Azenha et al., “Dermoscopy key points: recommendations from the international dermoscopy society,” Dermatology, vol. 214, no. 1, pp. 3–5, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. J. C. T. Braga, A. Scope, I. Klaz et al., “The significance of reflectance confocal microscopy in the assessment of solitary pink skin lesions,” Journal of the American Academy of Dermatology, vol. 61, no. 2, pp. 230–241, 2009. View at Publisher · View at Google Scholar · View at Scopus