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Dermatology Research and Practice
Volume 2010, Article ID 839829, 3 pages
Research Article

The Determination of Melanoma Stage at Diagnosis

Fred Hutchinson Cancer Research Center, M4-B874, 1100 Fairview Avenue N, Seattle, WA 98109, USA

Received 15 December 2009; Revised 11 March 2010; Accepted 26 May 2010

Academic Editor: Prashiela Manga

Copyright © 2010 John A. H. Lee. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The rising proportion of melanomas diagnosed at an early pathologic stage is commonly ascribed to better public education. However in the US SEER program of cancer registration it has been found that the rates for in situ melanomas are closely related by a log linear relationship to the incidence of invasive melanomas and that this relationship is unrelated to calendar year or gender or patient age. This relationship is sufficiently strong to leave little room for other factors. The relationship may be different in populations with different melanoma rates and responses to them. It is suggested that the results are due to variations within populations of individual response to melanoma cell proliferation.