Excoecarianin, Isolated from Phyllanthus urinaria Linnea, Inhibits Herpes Simplex Virus Type 2 Infection through Inactivation of Viral Particles
Figure 5
Synergistic antiviral activity of ACV and excoecarianin in Vero cells. IC50 values were derived from the data shown in Table 3 and used to construct the isobologram. FIC50 of ACV represents the ratio of the IC50 of ACV in the presence of a constant concentration of excoecarianin to the IC50 of ACV alone. The x-axis represents the ratio of the fixed concentration of excoecarianin to the IC50 of excoecarianin alone. In this representation, displacement of the experimental data points to the left of the theoretical line is indicative of synergistic behavior.
