Antidepressant-Like Activity of 10-Hydroxy-Trans-2-Decenoic Acid, a Unique Unsaturated Fatty Acid of Royal Jelly, in Stress-Inducible Depression-Like Mouse Model
Figure 3
Effects of HDEA on the anxiety (a) and locomotor activity (b) in the elevated plus-maze test for mice. The mice were treated with vehicle, HDEA, or fluvoxamine as described in the legend of Figure 2 and then subjected to the elevated plus-maze test at 24 hr after the end of the stress loading. Significance of differences from the values of mice without stress loading was determined by use of Student’s t-test (* as indicated by the bracket). Significant differences from the value of the vehicle-treated mice with stress loading were determined by performing one-way ANOVA with Tukey’s test (## as indicated by the brackets).
