Research Article

Antidepressant-Like Activity of 10-Hydroxy-Trans-2-Decenoic Acid, a Unique Unsaturated Fatty Acid of Royal Jelly, in Stress-Inducible Depression-Like Mouse Model

Figure 4

Effects of HDEA on the anxiety (a) and locomotor activity (b) in the open-field test for mice. The mice were treated with vehicle or HDEA as described in the legend of Figure 2 and then examined by the open-field test at 24 hr after the end of the stress. Significance of differences from the values of mice without stress loading was determined by using Student’s t-test (* as indicated by the bracket).
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(a)
139140.fig.004b
(b)