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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 156521, 18 pages
http://dx.doi.org/10.1155/2012/156521
Research Article

Mitigation of H2O2-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from Mesua kunstleri (King) Kosterm

1Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
3Faculty of Applied Sciences, Universiti Teknologi MARA, Selangor, 40450 Shah Alam, Malaysia
4Department of Aqidah and Islamic Thoughts, Academy of Islamic Studies, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 29 February 2012; Revised 16 April 2012; Accepted 20 April 2012

Academic Editor: Monica Rosa Loizzo

Copyright © 2012 Gomathi Chan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Tian-Biao Zhou, Yuan-Han Qin, Feng-Ying Lei, Wei-Fang Huang, and Gregor P. C. Drummen, “Prohibitin is associated with antioxidative protection in hypoxia/reoxygenation-induced renal tubular epithelial cell injury,” Scientific Reports, vol. 3, 2013. View at Publisher · View at Google Scholar
  • Muhamad Noor Alfarizal Kamarudin, Nur Afiqah Mohd Raflee, Sharifah Salwa Syed Hussein, Jia Ye Lo, Hadi Supriady, and Habsah Abdul Kadir, “(R)-(+)-alpha-Lipoic acid protected NG108-15 cells against H2O2-induced cell death through PI3K-Akt/GSK-3 beta pathway and suppression of NF-kappa beta-cytokines,” Drug Design Development and Therapy, vol. 8, pp. 1765–1780, 2014. View at Publisher · View at Google Scholar
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  • Noor Shahirah Suparji, Gomathi Chan, Norhafiza M. Arshad, Hani Sapili, Lionel L.A. In, Khalijah Awang, and Noor Hasima Nagoor, “Geranylated 4-phenylcoumarins exhibit anticancer effects against human prostate cancer cells through caspase-independent mechanism,” PLoS ONE, vol. 11, no. 3, 2016. View at Publisher · View at Google Scholar
  • Bassem Y. Sheikh, Md. Moklesur Rahman Sarker, Muhamad Noor Alfarizal Kamarudin, and Gokula Mohan, “Antiproliferative and apoptosis inducing effects of citral via p53 and ROS-induced mitochondrial-mediated apoptosis in human colorectal HCT116 and HT29 cell lines,” Biomedicine and Pharmacotherapy, vol. 96, pp. 834–846, 2017. View at Publisher · View at Google Scholar