Proteomic Analysis Reveals the Deregulation of Inflammation-Related Proteins in Acupuncture-Treated Rats with Asthma Onset
Figure 4
Protein expression profiles in lung tissues. (a) A representative 2DE gel image of proteins isolated from the AA group. The numerically labeled spots indicate the differentially expressed protein spots among the NC, AS, and AA groups. The numbers correspond to the spot identification numbers listed in Table 1. The molecular weight standards and pH range are shown at the left and bottom of the gels, respectively. (b) Differential expression profiles of five inflammation-related proteins regulated by acupuncture: CC10, S100A8, RAGE* (which is actually sRAGE, Table 1), RhoGDI2, and ANXA5. The cropped images of 2DE gels were symmetrically boxed, and the arrows on the images indicate the relative positions of the protein spots. (c) Quantitative analysis of the five inflammation-related proteins regulated by acupuncture. Each spot volume was quantified from the intensity of the spots using PDQuest software. The bars represent the mean ± SEM of triplicate 2DE gels. #, ## when comparing the AS group with the NC group. *, ** when comparing the AA group with the AS group.
