Antitumor Effects and Biological Mechanism of Action of the Aqueous Extract of the Camptotheca acuminata Fruit in Human Endometrial Carcinoma Cells

Table 1

Evaluation of tumor suppression efficiency of AE-CA on human endometrial carcinoma cells using the 50% inhibitory concentration (IC₅₀).

	HEC-1A				HEC-1B			KLE
AE-CA (mg/mL)	0.268				0.339			1.611
In comparison of AE-CA and CPT
	Con	Plus AE-CA	Plus CPT		Con	Plus AE-CA	Plus CPT
Cisplatin (μM)	60.114	4.101	20.969		33.111	4.879	4.013

IC₅₀ values for AE-CA in HEC-1AHEC-1A, HEC-1B, and KLE cells were calculated using the CalcuSyn software and based on the cytotoxicity data described in Figure 1.
IC₅₀ values for cisplatin alone (Con), cisplatin with AE-CA (plus AE-CA), and cisplatin with CPT (plus CPT) were calculated using the CalcuSyn software and based on the cytotoxicity data described in Figure 5.