Cobrotoxin from Naja naja atra Venom Ameliorates Adriamycin Nephropathy in Rats

Figure 6

The effects of CTX on the levels of IκB-α and p-IκB-α in ADR nephropathy rats. Rats were treated as described in caption of Figure 1. Rats were killed at 6th week and IκB-α (a) and p-IκB-α (c) expressions in renal tissue homogenates were determined with Western blot analysis (). Quantitative analyses of IκB-α (b) and p-IκB-α (d) levels were performed with ImageJ software and normalized to β-actin. Ratio of p-IκB-α to IκB-α (normalized to β-actin resp.) was calculated (e). , , and compared with “Control” group.

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