Research Article

Integrated Treatment of Aqueous Extract of Solanum nigrum-Potentiated Cisplatin- and Doxorubicin-Induced Cytotoxicity in Human Hepatocellular Carcinoma Cells

Table 1

IC50 values in HCC cells treated with AE-SN alone or in combination with AE-SN and either chemotherapeutic drug. The IC50 values were analyzed using cell viability data determined after 48 h treatment with AE-SN (Figure 2) and with AE-SN integrated with either chemotherapeutic drug (Figure 3).

Hep3BHep5J

AE-SN (mg/mL)0.960.97

Combination of AE-SN (mg/mL)
00.500.5

Cisplatin (μM)6.752.748.712.84
Doxorubicin (μM)4.651.316.391.42