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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 2046298, 14 pages
http://dx.doi.org/10.1155/2016/2046298
Research Article

Membrane Stabilization and Detoxification of Acetaminophen-Mediated Oxidative Onslaughts in the Kidneys of Wistar Rats by Standardized Fraction of Zea mays L. (Poaceae), Stigma maydis

1Phytomedicine and Phytopharmacology Research Group, Department of Plant Sciences, University of the Free State, QwaQwa Campus, Phuthaditjhaba 9866, South Africa
2Department of Microbial, Biochemical, and Food Biotechnology, University of the Free State, Nelson Mandela Drive, P.O. Box 339, Bloemfontein 9301, South Africa

Received 18 March 2016; Accepted 22 May 2016

Academic Editor: Khaled Abo-el-Sooud

Copyright © 2016 S. Sabiu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Ozbek, “Induction of oxidative stress in kidney,” International Journal of Nephrology, vol. 2012, Article ID 465897, 9 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. F. G. Silva, “Chemical-induced nephropathy: a review of the renal tubulointerstitial lesions in humans,” Toxicologic Pathology, vol. 32, no. 2, pp. 71–84, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. World Health Organization (WHO), Track Records of Global Chronic Kidney Disorders: An Update for the Sub-Saharan African Countries 2011–2014, DR: SSAFR/TR121/Doc, World Health Organization, Harare, Zimbabwe, 2014.
  4. National Kidney Foundation of South Africa (NKFS), “Fact sheet on the prevalence of kidney disorders,” 2015, http://www.nkf.org.za/kidney_disease.htm.
  5. Q. Z. Ahmad, N. Jahan, G. Ahmad, and G. Tajuddin, “An appraisal of nephroprotection and the scope of natural products in combating renal disorders,” Journal of Nephrology and Therapeutics, vol. 4, article 170, 2014. View at Publisher · View at Google Scholar
  6. World Health Organization, Preventing Chronic Disease: A Vital Investment, World Health Organization, Geneva, Switzerland, 2005.
  7. N. Ullah, M. A. Khan, T. Khan, and W. Ahmad, “Nephroprotective potentials of Citrus Aurantium: a prospective pharmacological study on experimental models,” Pakistan Journal of Pharmaceutical Sciences, vol. 27, no. 3, pp. 505–510, 2014. View at Google Scholar · View at Scopus
  8. N. Hamid and R. Mahmoud, “Tubular kidney protection by antioxidants,” Iranian Journal of Public Health, vol. 42, pp. 1194–1196, 2013. View at Google Scholar
  9. F. Grases, J. G. March, M. Ramis, and A. Costa-Bauzá, “The influence of Zea mays on urinary risk factors for kidney stones in rats,” Phytotherapy Research, vol. 7, no. 2, pp. 146–149, 1993. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Sabiu, F. H. O'Neill, and A. O. T. Ashafa, “Zea mays, Stigma maydis prevents and extenuates acetaminophen-perturbed oxidative onslaughts in rat hepatocytes,” Pharmaceutical Biology, 2016. View at Publisher · View at Google Scholar
  11. P. Guevara, M. C. Pérez-Amador, B. Zúñiga, and M. Snook, “Flavones in corn silks and resistance to insect attacks,” Phyton-International Journal of Experimental Botany, vol. 69, no. 1, pp. 151–156, 2000. View at Google Scholar · View at Scopus
  12. Z. A. Maksimović and N. Kovačević, “Preliminary assay on the antioxidative activity of Maydis stigma extracts,” Fitoterapia, vol. 74, no. 1-2, pp. 144–147, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. K. A. Kim, S.-K. Choi, and H.-S. Choi, “Corn silk induces nitric oxide synthase in murine macrophages,” Experimental and Molecular Medicine, vol. 36, no. 6, pp. 545–550, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. G.-Q. Wang, T. Xu, X.-M. Bu, and B.-Y. Liu, “Anti-inflammation effects of corn silk in a rat model of carrageenin-induced pleurisy,” Inflammation, vol. 35, no. 3, pp. 822–827, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. W. Zhao, Y. Yin, Z. Yu, J. Liu, and F. Chen, “Comparison of anti-diabetic effects of polysaccharides from corn silk on normal and hyperglycemia rats,” International Journal of Biological Macromolecules, vol. 50, no. 4, pp. 1133–1137, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Ghada, M. S. Eltohami, H. N. Adurahman, M. E. Mahmoud, and I. Mudawi, “In Vitro study of the effect of corn silk on glucose uptake by isolated rat hemi-diaphragm,” World Journal of Pharmaceutical Research, vol. 3, no. 4, pp. 2190–2195, 2014. View at Google Scholar
  17. E. Y. Sukandar, J. I. Sigit, and L. F. Adiwibowo, “Study of kidney repair mechanisms of corn silk (Zea mays L. Hair)-binahong (Anredera cordifolia (Ten.) Steenis) leaves combination in rat model of kidney failure,” International Journal of Pharmacology, vol. 9, no. 1, pp. 12–23, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. G. Sepehri, A. Derakhshanfar, and F. Y. Zadeh, “Protective effects of corn silk extract administration on gentamicin-induced nephrotoxicity in rat,” Comparative Clinical Pathology, vol. 20, no. 1, pp. 89–94, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. National Research Council (NRC), Guide for the Care and Use of Laboratory Animals, National Research Council, 8th edition, 2011.
  20. World Health Organization, Basic OECD Principles of GLP. Geneva, World Health Organization, Geneva, Switzerland, 1998.
  21. B. Parameshappa, M. S. Ali Basha, S. Sen et al., “Acetaminophen-induced nephrotoxicity in rats: protective role of Cardiospermum halicacabum,” Pharmaceutical Biology, vol. 50, no. 2, pp. 247–253, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. G. J. Schwartz, A. Muñoz, M. F. Schneider et al., “New equations to estimate GFR in children with CKD,” Journal of the American Society of Nephrology, vol. 20, no. 3, pp. 629–637, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. G. L. Ellman, “Tissue sulfhydryl groups,” Archives of Biochemistry and Biophysics, vol. 82, no. 1, pp. 70–77, 1959. View at Publisher · View at Google Scholar · View at Scopus
  24. P. J. Hissin and R. Hilf, “A fluorometric method for determination of oxidized and reduced glutathione in tissues,” Analytical Biochemistry, vol. 74, no. 1, pp. 214–226, 1976. View at Publisher · View at Google Scholar · View at Scopus
  25. C. A. Reilly and S. D. Aust, “Measurement of lipid peroxidation,” Current Protocols in Toxicology, vol. 2, pp. 2–4, 2001. View at Google Scholar · View at Scopus
  26. R. L Levine, D. Garland, C. N. Oliver, A. Amici, I. Climent, A. G. Lenz et al., Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants, Methods in Enzymology, Elsevier, Amsterdam, Netherlands, 1990.
  27. V. Witko-Sarsat, M. Friedlander, C. Capeillère-Blandin et al., “Advanced oxidation protein products as a novel marker of oxidative stress in uremia,” Kidney International, vol. 49, no. 5, pp. 1304–1313, 1996. View at Publisher · View at Google Scholar · View at Scopus
  28. K. Burton, “A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid,” The Biochemical journal, vol. 62, no. 2, pp. 315–323, 1956. View at Publisher · View at Google Scholar · View at Scopus
  29. H. P. Misra and I. Fridovich, “The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase,” The Journal of Biological Chemistry, vol. 247, no. 10, pp. 3170–3175, 1972. View at Google Scholar · View at Scopus
  30. H. Aebi, “Catalase in vitro,” Methods in Enzymology, vol. 105, pp. 121–126, 1984. View at Publisher · View at Google Scholar · View at Scopus
  31. R. A. B. Drury and E. A. Wallington, Carleton's Histological Techniques, Oxford University Press, New York, NY, USA, 5th edition, 1980.
  32. O. O. Oyedapo, B. A. Akinpelu, K. F. Akinwunmi, M. O. Adeyinka, and F. O. Sipeolu, “Red blood cell membrane stabilizing potentials of extracts of Lantana camara and its fractions,” International Journal of Plant Physiology and Biochemistry, vol. 2, no. 4, pp. 46–51, 2010. View at Google Scholar
  33. M. Hossain, S. Ahamed, S. M. Dewan et al., “In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves,” Biological Research, vol. 47, article 45, 2014. View at Publisher · View at Google Scholar
  34. M. Cekmen, Y. O. Ilbey, E. Ozbek, A. Simsek, A. Somay, and C. Ersoz, “Curcumin prevents oxidative renal damage induced by acetaminophen in rats,” Food and Chemical Toxicology, vol. 47, no. 7, pp. 1480–1484, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. S. Palani, S. Raja, R. P. Kumar, P. Parameswaran, and B. S. Kumar, “Therapeutic efficacy of Acorus calamus on acetaminophen induced nephrotoxicity and oxidative stress in male albino rats,” Acta Pharmaceutica Sciencia, vol. 52, no. 1, pp. 89–100, 2010. View at Google Scholar · View at Scopus
  36. A. L. Jones and L. F. Prescott, “Unusual complications of paracetamol poisoning,” Quarterly Journal of Medicine, vol. 90, no. 3, pp. 161–168, 1997. View at Publisher · View at Google Scholar · View at Scopus
  37. C. Lorz, P. Justo, A. Sanz, D. Subirá, J. Egido, and A. Ortiz, “Paracetamol-induced renal tubular injury: a role for ER stress,” Journal of the American Society of Nephrology, vol. 15, no. 2, pp. 380–389, 2004. View at Publisher · View at Google Scholar
  38. A. A. Adeneye and A. S. Benebo, “Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats,” Journal of Ethnopharmacology, vol. 118, no. 2, pp. 318–323, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. M. T. Yakubu, L. S. Bilbis, M. Lawal, and M. A. Akanji, “Evaluation of selected parameters of rat liver and kidney function following repeated administration of yohimbine,” Biochemistry, vol. 15, pp. 50–56, 2003. View at Google Scholar
  40. O. B. Oloyede and T. O. Sunmonu, “Potassium bromate content of selected bread samples in Ilorin, Central Nigeria and its effect on some enzymes of rat liver and kidney,” Food and Chemical Toxicology, vol. 47, no. 8, pp. 2067–2070, 2009. View at Publisher · View at Google Scholar · View at Scopus
  41. D. G. Shirley and R. J. Unwin, “The structure and function of tubules,” in The Oxford Textbook of Clinical Nephrology, A. M. Davison, S. J. Cameron, J. P. Grunfeld et al., Eds., Oxford University Press, Oxford, UK, 3rd edition, 2005. View at Google Scholar
  42. A. Devine, R. A. Criddle, I. M. Dick, D. A. Kerr, and R. L. Prince, “A longitudinal study of the effect of potassium, sodium and calcium intake on regional bone density in post-menopausal women,” American Journal of Clinical Nutrition, vol. 18, pp. 3735–3785, 1999. View at Google Scholar
  43. S. I. Alqasoumi, “Evaluation of the hepatroprotective and nephroprotective activities of Scrophularia hypericifolia growing in Saudi Arabia,” Saudi Pharmaceutical Journal, vol. 22, no. 3, pp. 258–263, 2014. View at Publisher · View at Google Scholar · View at Scopus
  44. S. Sireeratawong, N. Lertprasertsuke, U. Srisawat et al., “Acute and subchronic toxicity study of the water extract from Tiliacora triandra (Colebr.) Diels in rats,” Songklanakarin Journal of Science and Technology, vol. 30, no. 5, pp. 611–619, 2008. View at Google Scholar · View at Scopus
  45. S. Saheed, A. E. Oladipipo, A. A. Abdulazeez et al., “Toxicological evaluations of Stigma maydis (corn silk) aqueous extract on hematological and lipid parameters in Wistar rats,” Toxicology Reports, vol. 2, pp. 638–644, 2015. View at Publisher · View at Google Scholar · View at Scopus
  46. Z. Abdul Hamid, B. B. Siti, N. W. Jie, H. Asmah, H. Khairana, and M. Jamaludin, “Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats,” Journal of Zhejiang University of Science (Biotechnology and Biomedicine), vol. 13, no. 3, pp. 176–185, 2012. View at Publisher · View at Google Scholar
  47. A. Wooley, A Guide to Practical Toxicology Evaluation, Prediction and Risk Determination in General and Reproductive Toxicology, Taylor & Francis, New York, NY, USA, 2003.
  48. G. R. Amresh, P. N. Singh, and C. V. Rao, “Toxicological screening of traditional medicine Laghupatha (Cissampelos pareira) in experimental animals,” Journal of Ethnopharmacology, vol. 116, no. 3, pp. 454–460, 2008. View at Publisher · View at Google Scholar · View at Scopus
  49. J. Das, J. Ghosh, P. Manna, and P. C. Sil, “Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation,” Toxicology, vol. 269, no. 1, pp. 24–34, 2010. View at Publisher · View at Google Scholar · View at Scopus
  50. M. I. Yousef, S. A. M. Omar, M. I. El-Guendi, and L. A. Abdelmegid, “Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat,” Food and Chemical Toxicology, vol. 48, no. 11, pp. 3246–3261, 2010. View at Publisher · View at Google Scholar · View at Scopus
  51. K. R. Basma and F. S. Mona, “The renoprotective effect of honey on paracetamol-induced nephrotoxicity in adult male albino rats,” Life Science Journal, vol. 8, no. 3, pp. 8–12, 2011. View at Google Scholar
  52. S. Palani, S. Raja, K. R. Praveen, J. Soumya, and K. B. Senthil, “Therapeutic efficacy of Pimpinella tirupatiensis (Apiaceae) on acetaminophen induced nephrotoxicity and oxidative stress in male albino rats,” International Journal of Pharmacy and Technology Research, vol. 1, no. 3, pp. 925–934, 2009. View at Google Scholar
  53. N. Kaplowitz, “Mechanisms of liver cell injury,” Journal of Hepatology, vol. 32, supplement 1, pp. 39–47, 2000. View at Google Scholar · View at Scopus
  54. P. I. Margetis, M. H. Antonelou, I. K. Petropoulos, L. H. Margaritis, and I. S. Papassideri, “Increased protein carbonylation of red blood cell membrane in diabetic retinopathy,” Experimental and Molecular Pathology, vol. 87, no. 1, pp. 76–82, 2009. View at Publisher · View at Google Scholar · View at Scopus
  55. C. J. J. Alderman, S. Shah, J. C. Foreman, B. M. Chain, and D. R. Katz, “The role of advanced oxidation protein products in regulation of dendritic cell function,” Free Radical Biology and Medicine, vol. 32, no. 5, pp. 377–385, 2002. View at Publisher · View at Google Scholar · View at Scopus
  56. M. S. Cooke, M. D. Evans, M. Dizdaroglu, and J. Lunec, “Oxidative DNA damage: mechanisms, mutation, and disease,” The FASEB Journal, vol. 17, no. 10, pp. 1195–1214, 2003. View at Publisher · View at Google Scholar · View at Scopus
  57. H. Jaeschke and M. L. Bajt, “Intracellular signaling mechanisms of acetaminophen-induced liver cell death,” Toxicological Sciences, vol. 89, no. 1, pp. 31–41, 2006. View at Publisher · View at Google Scholar · View at Scopus
  58. D. Brahmi, C. Bouaziz, Y. Ayed, H. Ben-Mansour, L. Zourgui, and H. Bacha, “Chemopreventive effect of cactus Opuntia ficus indica on oxidative stress and genotoxicity of aflatoxin B1,” Nutrition & Metabolism, vol. 8, article 73, 2011. View at Publisher · View at Google Scholar · View at Scopus
  59. H. Parlakpinar, S. Tasdemir, A. Polat et al., “Protective role of caffeic acid phenethyl ester (cape) on gentamicin-induced acute renal toxicity in rats,” Toxicology, vol. 207, no. 2, pp. 169–177, 2005. View at Publisher · View at Google Scholar · View at Scopus
  60. M. Aslam, S. T. Ahmad, R. Dayal et al., “Nephroprotective action of Peucedanum grande against cadmium chloride induced renal toxicity in Wistar rats,” EXCLI Journal, vol. 11, pp. 444–452, 2012. View at Google Scholar · View at Scopus
  61. F. A. Kadir, N. M. Kassim, M. A. Abdulla, and W. A. Yehye, “Effect of oral administration of ethanolic extract of Vitex negundo on thioacetamide-induced nephrotoxicity in rats,” BMC Complementary and Alternative Medicine, vol. 13, article 294, 2013. View at Publisher · View at Google Scholar · View at Scopus
  62. E. Marieb, “Urinary system,” in Essentials of Human Anatomy and Physiology, pp. 501–526, Pearson Benjamin Cummings, San Fransisco, Calif, USA, 8th edition, 2006. View at Google Scholar
  63. M. Naggayi, N. Mukiibi, and E. Iliya, “The protective effects of aqueous extract of Carica papaya seeds in paracetamol induced nephrotoxicity in male wistar rats,” African Health Sciences, vol. 15, no. 2, pp. 598–605, 2015. View at Publisher · View at Google Scholar · View at Scopus
  64. S. Umukoro and R. B. Ashorobi, “Evaluation of anti-inflammatory and membrane stabilizing property of aqueous leaf extract of Momordica charantia in rats,” African Journal of Biomedical Research, vol. 9, no. 2, pp. 119–124, 2009. View at Publisher · View at Google Scholar
  65. O. O. Amujoyegbe, J. M. Agbedahunsi, B. A. Akinpelu, and O. O. Oyedapo, “In vitro evaluation of membrane stabilizing activities of leaf and root extracts of Calliandra portoricensis (JACQ) benth on sickle and normal human erythrocytes,” International Research Journal of Pharmacy and Pharmacology, vol. 2, no. 8, pp. 198–203, 2012. View at Google Scholar
  66. I. Khan, M. Nisar, F. Ebad et al., “Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies,” Journal of Ethnopharmacology, vol. 121, no. 1, pp. 175–177, 2009. View at Publisher · View at Google Scholar · View at Scopus
  67. S. Sabiu, F. H. O'Neill, and A. O. T. Ashafa, “Kinetics of α-amylase and α-glucosidase inhibitory potential of Zea mays Linnaeus (Poaceae), Stigma maydis aqueous extract: an in vitro assessment,” Journal of Ethnopharmacology, vol. 183, pp. 1–8, 2016. View at Publisher · View at Google Scholar · View at Scopus