Evidence-Based Complementary and Alternative Medicine / 2016 / Article / Tab 4

Research Article

Synergistic Effect of Ferulic Acid and Z-Ligustilide, Major Components of A. sinensis, on Regulating Cold-Sensing Protein TRPM8 and TPRA1 In Vitro

Table 4

Combination index (CI) at ED70, ED75, and ED90 values with drug combination on inhibiting cold-induced upregulation of TRPM8 expression. The CI values at Fa value of 0.70, 0.75, and 0.90 for isobolograms (Figure 5(c)) were calculated.

Drug (ratio)CI values at

FA : lig (3.416 : 2.325)0.149430.168790.28823

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