Research Article

Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L.

Table 3

Effect of Tamarindus indica L. tablets on serum biochemical markers of liver function in CCl4 induced hepatotoxicity in Sprague Dawley rats.

GroupALT (UI/L)AST (UI/L)ALP (UI/L)GGT (UI/L)TB (mg/100 mL)TP (g/100 mL)

I32.56 2.0521.37 0.59187.32 3.0886.18 3.863.09 0.047.12 0.47
II326.78 19.3195.97 4.41426.53 3.31161.30 7.906.57 0.095.26 0.37
III36.33 0.9437.27 5.64204.56 2.9098.10 1.404.84 0.258.29 0.22
IV38.62 0.9838.67 2.50246.76 3.10111.10 1.195.21 0.177.41 0.23
V33.49 0.9125.38 2.38202.51 4.9699.09 3.345.15 0.068.33 0.34

ALT: alanine aminotransferase, AST: aspartate aminotransferase, ALP: alkaline phosphatase, GGT: -glutamyl transpeptidase, TB: total bilirubin, and TP: total protein.
I: control group; II: CCl4 induced hepatotoxicity group; III: Silymarin treated group; IV and V: Tamarindus indica L. tablets treated groups at doses 100 mg/kg and 200 mg/kg, respectively.
Different letters on columns indicate significant statistical differences in Tukey HSD test.
Data are expressed as mean SD; .