Evidence-Based Complementary and Alternative Medicine

Research Article

Medicinal Plants from Northeastern Brazil against Alzheimer’s Disease

Table 2

Antioxidant activity (DPPH, ABTS, and β-carotene/linoleic acid tests), phenolics content, flavonoid content, and acetylcholinesterase inhibitory activity of selected medicinal plant species used in the northeast region of Brazil.


Species	DPPH μg/mL	β-Carotene μg/mL	ABTS μg/mL	Phenols Mg GAE/g extract	Flavonoids mg EQ/g extract	AChEI IC₅₀ μg/mL

Ap	53.65 ± 0.24	12.51 ± 0.66	2.12 ± 0.01	62.23 ± 0.15	0.88 ± 0.04	397.23 ± 0.09
Bf	49.39 ± 0.47	13.72 ± 0.22	3.44 ± 0.01		4.62 0.03	10.90 ± 1.44
Cl	45.23 ± 0.17	13.74 ± 0.99	2.64 ± 0.02	48.03 ± 0.30	4.35 ± 0.01	14.86 ± 1.79
Eo	28.54 ± 0.78	22.09 ± 0.81	2.04 ± 0.17	51.10 ± 0.59	1.31 ± 0.06	130.29 ± 0.37
Hs	30.70 ± 0.68	5.73 ± 0.38	2.18 ± 0.06	60.26 ± 0.45	8.64 ± 0.02	10.13 ± 0.17
Ld	38.48 ± 0.53	10.77 ± 0.55	3.98 ± 0.11	55.81 ± 0.39	0.83 ± 0.04	111.54 ± 0.33
Mi	50.78 ± 0.47	1.18 ± 0.16	2.13 ± 0.05	28.79 ± 1.16	13.51 ± 0.04	29.67 ± 0.42
Mu	48.01 ± 0.35	6.92 ± 1.42	2.14 ± 0.02	61.28 ± 0.44	0.96 ± 0.03	10.75 ± 0.15
Pr	51.33 ± 0.34	19.67 ± 0.36	3.93 ± 0.21	61.56 ± 0.27	0.91 ± 0.01	46.93 ± 0.76
Pg	40.42 ± 0.81	15.06 ± 0.40	2.22 ± 0.06	37.85 ± 0.53	3.82 ± 0.02	18.98 ± 0.11
Sc	45.09 ± 0.15	13.71 ± 0.21	1.96 ± 0.05	52.85 ± 0.02	1.05 ± 0.01	17.56 ± 0.50
Sa	56.54 ± 0.99	8.81 ± 0.26	4.00 ± 0.07	91.27 ± 0.26	2.02 ± 0.01	152.25 ± 0.04
Ru	39.20 ± 0.16	9.25 ± 0.01	2.05 ± 0.08	—	—	—
Es	—	—	—	—	—	19.53 ± 0.08

The data are presented as the mean ± standard deviation and were analyzed using ANOVA followed by a Tukey test. Values with different superscript letters are significantly different (). Flavonoid content: mg EQ/g extract; phenolic compounds content: mg GAE/g extract; 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis-3-ethylbenzothiazoline-6-sulfonate (ABTS), β-carotene/linoleic acid, and acetylcholinesterase inhibition (AChEI): IC₅₀ (μg/mL). Ap, Anadenanthera peregrina (bark); Bf, Bauhinia forficata (bark); Cl, Copaifera langsdorffii (bark); Eo, Euterpe oleracea (seeds), Hs, Hancornia speciosa (bark); Ld, Luehea divaricata (leaves); Mi, Mangifera indica (leaves); Mu, Myracrodruon urundeuva (bark); Pr, Plathymenia reticulata (leaves); Pg, Psidium guajava (leaves); Sc, Stryphnodendron coriaceum (bark); Sa, Syzygium aromaticum (fruits); Ru, rutin (antioxidant control); Es, eserine (acetylcholinesterase control); —: not performed.