Therapeutic Effects of Fermented Flax Seed Oil on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Figure 4

Regulation of Th2 differentiation. (a) Ratio of IL-6 to GAPDH expression in cells was determined by real-time PCR. Real-time PCR product-stimulated macrophages were analyzed as described in Section 2. Data were expressed as the mean ± SD of two separate experiments. (b) Expression of IL-4 and IL-6 (arrow indicates dark brown) in cells decreased in the AT group compared with the AE group (IL-4 and IL-6 immunohistochemistry; Bar size, 50 µm). EP: epidermis, DE: dermis. STAT6 and STAT3 expression (arrow indicates dark brown) in cells decreased in the AT group compared with the AE group (STAT6 and STAT3 immunohistochemistry; Bar size, 50 µm). Abbreviations are the same as in Figure 1. compared with AE; compared with Ctrl.

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