Therapeutic Effects of Fermented Flax Seed Oil on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Figure 5

Maintenance of lipid barrier in epidermis. LXR expression (arrow indicates dark brown) remarkably decreased in the AE group but was maintained in the AT group (LXR immunohistochemistry; Bar size, 50 µm). The lipid barrier (arrow indicates bright blue) in the intercellular space from the stratum granulosum to stratum corneum was absent in the AE group but present in the AT group (Sudan black B; Bar size, 50 µm). PKC expression (arrow indicates dark brown) in the AE group remarkably decreased (PKC immunohistochemistry; Bar size, 50 µm). LXR: liver X receptor, PKC: Protein kinase C; other abbreviations are the same as in Figure 1.