A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement

Table 2

Comparison within groups after 12 weeks of both groups.

Vancouver Scar Scale	Centella cream	Contrast	95% CI	P-value
After	week 4th	0.400	-0.799 - 1.599	0.510
After	week 8th	-0.089	-1.312 - 1.133	0.885
After	week 12th	-0.879	-2.102 - 0.344	0.157
Between	8&4 weeks	-0.489	-1.712 - 0.733	0.429
Between	12&4 weeks	-1.279	-2.502 - -0.056	0.041
Between	12&8 weeks	-0.789	-2.020 - 0.441	0.206
Vancouver Scar Scale	Placebo
After	week 4th	0.150	-1.049 - 1.349	0.805
After	week 8th	0.312	-0.911 - 1.535	0.614
After	week 12th	-0.793	-2.016 - 0.429	0.201
Between	8&4 weeks	0.162	-1.061 - 1.385	0.794
Between	12&4 weeks	-0.943	-2.166 - 0.279	0.129
Between	12&8 weeks	-1.105	-2.336 - 0.125	0.078
Vascularity	Centella cream
After	week 4th	0.100	-0.426 - 0.626	0.707
After	week 8th	-0.055	-0.591 - 0.481	0.838
After	week 12th	-0.213	-0.749 - 0.323	0.432
Between	8&4 weeks	-0.155	-0.691 - 0.381	0.567
Between	12&4 weeks	-0.313	-0.849 - 0.223	0.249
Between	12&8 weeks	-0.158	-0.697 - 0.381	0.563
Vascularity	Placebo
After	week 4th	-0.050	-0.576 - 0.476	0.851
After	week 8th	-0.051	-0.587 - 0.485	0.850
After	week 12th	-0.367	-0.903 - 0.169	0.177
Between	8&4 weeks	-0.001	-0.537 - 0.535	0.996
Between	12&4 weeks	-0.317	-0.853 - 0.219	0.244
Between	12&8 weeks	-0.316	-0.855 - 0.224	0.248
Pigmentation	Centella cream
After	week 4th	-0.150	-0.478 - 0.178	0.366
After	week 8th	-0.443	-0.777 - -0.109	0.010
After	week 12th	-0.707	-1.041 - -0.373	0.001
Between	8&4 weeks	-0.293	-0.627 - 0.041	0.084
Between	12&4 weeks	-0.557	-0.891 - -0.223	0.001
Between	12&8 weeks	-0.263	-0.599 - 0.073	0.124
Pigmentation	Placebo
After	week 4th	-0.150	-0.478 - 0.178	0.366
After	week 8th	-0.233	-0.567 - 0.101	0.170
After	week 12th	-0.549	-0.883 - -0.215	0.002
Between	8&4 weeks	-0.083	-0.417 - 0.251	0.624
Between	12&4 weeks	-0.399	-0.733 - -0.065	0.020
Between	12&8 weeks	-0.316	-0.652 - 0.020	0.065
Pliability	Centella cream
After	week 4th	0.200	-0.202 - 0.602	0.326
After	week 8th	0.179	-0.231 - 0.589	0.389
After	week 12th	-0.137	-0.547 - 0.273	0.509
Between	8&4 weeks	-0.021	-0.431 - 0.389	0.919
Between	12&4 weeks	-0.337	-0.747 - 0.073	0.106
Between	12&8 weeks	-0.316	-0.728 - 0.097	0.132
Pliability	Placebo
After	week 4th	0.150	-0.252 - 0.552	0.461
After	week 8th	0.312	-0.098 - 0.722	0.134
After	week 12th	-0.004	-0.414 - 0.406	0.985
Between	8&4 weeks	0.162	-0.248 - 0.572	0.435
Between	12&4 weeks	-0.154	-0.564 - 0.256	0.458
Between	12&8 weeks	-0.316	-0.728 - 0.097	0.132
Height	Centella cream
After	week 4th	0.300	0.009 - 0.591	0.043
After	week 8th	0.229	-0.067 - 0.525	0.129
After	week 12th	0.176	-0.120 - 0.473	0.241
Between	8&4 weeks	-0.071	-0.367 - 0.225	0.636
Between	12&4 weeks	-0.124	-0.420 - 0.173	0.410
Between	12&8 weeks	-0.053	-0.351 - 0.246	0.727
Height	Placebo
After	week 4th	0.200	-0.091 - 0.491	0.176
After	week 8th	0.284	-0.012 - 0.581	0.060
After	week 12th	0.126	-0.170 - 0.423	0.400
Between	8&4 weeks	0.084	-0.212 - 0.381	0.575
Between	12&4 weeks	-0.074	-0.370 - 0.223	0.623
Between	12&8 weeks	-0.158	-0.456 - 0.140	0.296