Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis

Table 1

Phenolic compounds identified in the hydroethanolic extract of fruits of Vaccinium macrocarpon (HEVm) by HPLC-DAD-ESI-MS/MS.

Peak	Proposed structure	RT (min)	Molecular ion	MS^2/MS^3 (m/z)	Concentration
1	Catechin	14,9	291	273; 165; 139; 123	581,82 ± 30,50
2	Epicatechin	18,5	291	273; 165; 139; 123	95,70 ± 4,01
3	Quercetin-3-O-rutinoside	24,5	611	465; 303	37,89 ± 6,55
4	Epicatechin gallate	24,8	441	289; 169	139,22 ± 5,07
5	Cyanidin-3-O-galactoside	13.4	449	287	2,45 ± 0,45
6	Cyanidin-3-O-glucoside	14.4	449	287	11,87 ± 0,75
7	Cyanidin-coumaroyl-hexoside	14.7	595	449/287	6,69 ± 0,54

RT, retention time. Peaks are numbered according to Figures 1(a) and 1(b). Compounds’ identity was confirmed by comparison with RT of standards and mass fragment profile and UV-Vis absorption spectra. Expressed as mean ± SD of mg/100 g of extract. Quantified as equivalent of epicatechin. Quantified as equivalent of cyanidin-3-O-glucoside. Compounds 1–3 and 4–7 were analyzed in positive mode; compound 4 was analyzed in negative mode.