Metabolic and Epigenetic Action Mechanisms of Antidiabetic Medicinal Plants

Figure 3

Contribution of the major tissues to the glycemic control via insulin-dependent Akt and insulin-independent AMPK signaling cascades [14]. AMPK: AMP-activated protein kinase; Akt: protein kinase B; CEBP: Ccaat-enhancer binding protein; GLUT: glucose transporter; ACC: acetyl-CoA carboxylase; SREPB-1: sterol regulatory element binding protein 1; G6Pase: glucose-6-phosphatase; GSK: glycogen synthase kinase; GS: glycogen synthase. Figure 3 is reproduced from Saad et al. (2017) ([under the Creative Commons Attribution License/public domain)” [14].