Cardioprotective Effect of Danhong Injection against Myocardial Infarction in Rats Is Critically Contributed by MicroRNAs

Figure 1

Effects of DHI on cardiac functionality and hemodynamics index. Quantitative assessment of dilation and systolic function based on LVEF (LV ejection fraction) (a), LVIDs (LV end-systolic dimensions) (b), LVAWs (LV end-systolic anterior walls) (c), LVFS (LV fractional shortening) (d), LVVols (LV systolic volumes) (e), Tei value ((IVCT + ICRT)/MVET) (f), isovolumic contraction time plus isovolumic relaxation time (IVCT + IVRT), mitral valve ejection time (MVET), and LVSP (LV systolic pressure) (g), LVEDP (LV end-diastolic pressure) (h), +dp/dt max (LV maximum upstroke velocity) (i), −dp/dt max (LV maximum descent velocity) (j), HR (heart rate) (k), and SW (stroke work) (l). Representative echocardiographic images (M mode) in different groups (m). From left to right: sham group, model group, DHI group, valsartan group. All values are means ± SD (n = 8 or n = 6). and versus sham group; and versus model group.

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