Cardioprotective Effect of Danhong Injection against Myocardial Infarction in Rats Is Critically Contributed by MicroRNAs

Figure 6

Effect of DHI on the activation of the NF-κB pathway. (a) DHI inhibits phosphorylation of NF-κB and IκB-α in cardiomyocytes cytoplasm from infarct marginal zone. (b) DHI prevents the nucleation of NF-κB in myocardial tissue from the infarct marginal zone. The level of p-NFκB and p-IκB-α in the cytoplasm was corrected by NF-κB and IκB-α, respectively. The expression of NF-κB in the nucleus was corrected by Lamin B. Data are expressed as mean ± SD (n = 3). compared with the sham group; compared with the model group.

(a)

(b)