Research Article

Spinal Cord Glycine Transporter 2 Mediates Bilateral ST35 Acupoints Sensitization in Rats with Knee Osteoarthritis

Figure 5

GlyT2 but not GlyT1 was increased in the left KOA rats. ((a) and (b)) Expression of GlyT1 and GlyT2 in bilateral L3-L5 spinal cord dorsal horn at 14 days after MIA or saline injection. P < 0.01 versus Control-L group; ##P < 0.01 versus Control-R group; n = 6 per group. (c) Representative fluorescent staining images (green fluorescence) of GlyT2 expression in the spinal cord dorsal horn at L3-5 in control and MIA rats. (d) Mean gray value of GlyT2 expression in L3-L5, laminae I-III. Scale bar is 100 μm; P < 0.01 versus Control-L group; ##P < 0.01 versus Control-R group; n = 8 per group. All data are presented as the mean ± SEM; one-way ANOVA followed by Tukey’s post hoc test was used.
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