Spinal Cord Glycine Transporter 2 Mediates Bilateral ST35 Acupoints Sensitization in Rats with Knee Osteoarthritis

Figure 8

Downregulation of GlyT2 by GlyT2-shRNA partially reversed EA-induced analgesia in KOA rats. (a) Representative H&E staining for articular pathology in each group. The scale bar is 200 μm. (b) OARSI scores are presented as the mean ± SD; Kruskal-Wallis test was used, P < 0.01 versus MIA group; ^#P < 0.05 versus MIA group; n = 8 per group. ((c) and (d)) Paw withdrawal mechanical thresholds of the ipsilateral hind paw and weight-bearing deficits were assessed. Data are presented as the mean ± SEM; two-way repeated measures ANOVA followed by Bonferroni’s post hoc test was used.

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