Research Article

Scrodentoids H and I, a Pair of Natural Epimerides from Scrophularia dentata, Inhibit Inflammation through JNK-STAT3 Axis in THP-1 Cells

Figure 7

The effect of SP600125 on mRNA of IL-1β and IL-6. (a, b) THP-1 cells were pretreated with various concentrations of SP600125 (0∼10 μM) for 1 h following treatment of LPS (1 μg/mL) for 4 h, and total RNA was extracted to detect relative mRNA levels. All data are mean ± SEM, n = 3, vs. LPS-stimulated cells and vs. control.