2-(6-Hydroxyhexylthio)-5,8-dimethoxy-1,4-naphthoquinone Induces Apoptosis through ROS-Mediated MAPK, STAT3, and NF-κB Signalling Pathways in Lung Cancer A549 Cells

Figure 5

Effects of HHDMNQ on the MAPK, STAT3, and NF-κB signalling pathways in A549 cells. (a–e) A549 cells treated with 6 μM HHDMNQ for 3, 6, 12, and 24 h. Expression levels of p38, ERK, JNK, STAT3, NF-κB (p65), and IκB-α were analyzed by western blot and quantification histograms of proteins (, , ).

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