Antidiabetic Potential of Prosopis farcta Roots: In Vitro Pancreatic Beta Cell Protection, Enhancement of Glucose Consumption, and Bioassay-Guided Fractionation
Table 1
Effect of various fractions of the root extract of P. farcta on the viability of β-TC3 cells.
Fractions
Concentrations (mg/mL)
0.01
0.05
0.1
0.5
F1
96.0 ± 8
98.0 ± 7.0
100.0 ± 7.0
108.0 ± 9.0
F2
103.0 ± 8.7
105.0 ± 10
107.0 ± 6.0
110.0 ± 8.0
F3
92 ± 9
93.0 ± 9.7
97.0 ± 8.0
107.0 ± 4.0
F4
104.0 ± 4.75
107.3 ± 4.6
108.1 ± 5.2
109.0 ± 6.1
F5
94.7 ± 8.18
96.2 ± 5.6
98.32 ± 5.38
103.2 ± 6.1
F6
95.2 ± 3.8
104.2 ± 4.14
108 ± 4.1
110.0 ± 6
F7
105.53 ± 8
108.6 ± 6.35
110.3 ± 6.98
114.8 ± 7.2
F2A
89.9 ± 7.34
96.9 ± 15
105 ± 4.14
114.2 ± 7.8
F2B
87.9 ± 8.3
90.0 ± 10.7
96.94 ± 7.82
98.07 ± 6.6
F2C
91.0 ± 8.7
103.0 ± 8.0
111.7 ± 6.0
115 ± 8.0
F2D
96.3 ± 3.2
98.07 ± 4.5
95 ± 7.4
112.56 ± 8.5
F2C-a
88.8 ± 3.7
88.23 ± 6.9
86.8 ± 6.5
84.8 ± 4.6
F2C-b
84.31 ± 7.1
85.27 ± 5.2
84.5 ± 5.5
87.7 ± 2.7
F2C-c
92.1 ± 7.5
96.4 ± 7.0
88.7 ± 12.0
94.7 ± 9.3
F2C-d
93.9 ± 6.5
97.0 ± 8.28
99.0 ± 10.23
108.5 ± 14.0
Cell viability was determined by the MTT assay after 24 h of treatment with the various fractions. Data are expressed as the mean ± SD of three separate experiments and were not significantly different from the untreated control group at the level of .
