Suhuang Antitussive Capsule Ameliorates Corticosteroid Insensitivity in Cough Variant Asthma Guinea Pigs by Inhibiting p38 MAPK Signal Pathway

Figure 5

Pathological changes of lung tissues. H&E staining slices from lung sections, magnification 100×. (a) Control group, (b) OVA group, (c) OVA + CS group, (d) Suhuang treatment group, (e) BUD treatment group, and (f) combination treatment group. In Figures 5(b) and (5c), we observe widening of alveolar septum (red arrows), destruction of alveolar structure (yellow arrows), dilation of tracheal lumen (green arrows), proliferation or flatness of mucosal folds (black arrows), and aggregation of inflammatory cells (blue arrows). In Figures 5(d)–5(f), we observe widening of alveolar septum (red arrows), destruction of alveolar structure (yellow arrows), dilation of tracheal lumen (green arrows), proliferation or flatness of mucosal folds (black arrows), and aggregation of inflammatory cells are reduced.

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