Research Article
Prevalence and Risk Factors Comparison of Anterior and Posterior Intracranial Arterial Stenosis
Table 2
ORs and 95% CIs of ICAS for 3600 individuals free of stroke
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| | Risk factors | Anterior circulation | Posterior circulation | | Crude OR and 95% CI | Fully adjusted OR and 95% CI | Crude OR and 95% CI | Fully adjusted OR and 95% CI |
| | Age (<65 vs. ≥65 years old) | 1.79 (1.48∼2.17) | 1.18 (0.93∼1.47) | 3.37 (2.46∼4.61) | 2.16 (1.48∼3.15) | | Gender (male vs. female) | 0.89 (0.73∼1.07) | 0.88 (0.66∼1.17) | 1.07 (0.80∼1.43) | 1.04 (0.68∼1.61) | | Hypertension (no vs. yes) | 1.99 (1.65∼2.41) | 1.79 (1.40∼2.27) | 3.35 (2.49∼4.50) | 2.54 (1.76∼3.69) | | Diabetes (no vs. yes) | 1.76 (1.42∼2.17) | 1.35 (1.04∼1.75) | 2.42 (1.80∼3.25) | 1.71 (1.19∼2.46) | | Hyperlipidemia (no vs. yes) | 1.12 (0.93∼1.36) | 1.05 (0.83∼1.32) | 1.52 (1.13∼2.04) | 1.49 (1.04∼2.16) | | History of CAD (no vs. yes) | 2.00 (1.32∼3.01) | 1.23 (0.71∼2.12) | 3.72 (2.30∼6.00) | 1.86 (0.97∼3.56) | | Smoking status | | | | | | Never | Reference | Reference | Reference | Reference | | Current smoker | 1.06 (0.84∼1.34) | 1.00 (0.71∼1.39) | 0.97 (0.68∼1.39) | 1.25 (0.75∼2.08) | | Ex-smoker | 1.38 (1.02∼1.88) | 1.22 (0.81∼1.83) | 1.19 (0.74∼1.91) | 1.02 (0.54∼1.92) | | Normal weight | Reference | Reference | Reference | Reference | | Underweight | 0.83 (0.35∼1.97) | 1.19 (0.45∼3.13) | 0.61 (0.15∼2.57) | 0.96 (0.22∼4.20) | | Overweight | 1.01 (0.83∼1.23) | 0.93 (0.73∼1.18) | 0.82 (0.61∼1.11) | 0.61 (0.42∼0.88) | | Obese | 0.87 (0.63∼1.20) | 0.61 (0.40∼0.92) | 0.69 (0.42∼1.15) | 0.33 (0.17∼0.65) | | Hyperuricaemia (no vs. yes) | 1.31 (1.02∼1.68) | 1.17 (0.87∼1.58) | 1.65 (1.17∼2.33) | 1.07 (0.69∼1.67) | | Hyperhomocysteinemia (no vs. yes) | 0.99 (0.80∼1.22) | 0.94 (0.74∼1.18) | 1.04 (0.76∼1.44) | 0.94 (0.66∼1.34) | | hi-CRP(mg/dl) | | | | | | 1st tertile (≤0.70) | Reference | Reference | Reference | Reference | | 2nd tertile (0.71–1.80) | 0.77 (0.61∼0.98) | 1.02 (0.77∼1.35) | 0.84 (0.58∼1.20) | 1.07 (0.68∼1.67) | | 3rd tertile (>1.80) | 0.98 (0.78∼1.22) | 1.27 (0.97∼1.67) | 1.37 (1.00∼1.89) | 1.69 (1.12∼2.56) | | UMA (no vs. yes) | 1.21 (0.99∼1.47) | 1.27 (0.97∼1.67) | 1.59 (1.19∼2.12) | 1.23 (0.87∼1.75) |
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Population with neither ICAS nor stroke was the reference group, and the frequencies of risk factors are listed in Supplementary Table S3. |
