Evidence-Based Complementary and Alternative Medicine

Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention


Publishing date
21 Feb 2014
Status
Published
Submission deadline
04 Oct 2013

Lead Editor

1Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan

2Graduate Institute of Applied Living Science, Tainan University of Technology, Tainan City, Taiwan

3Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

4Tissue Culture Center, New York Eye and Ear Infirmary, New York Medical College, New York City, NY, USA


Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention

Description

Natural bioactives or phytochemicals is generally referred to the compounds exclusive of essential nutrients that have specific biological activity to human. It has been known that over 10,000 different phytochemicals possess the potential preventive or supplementary effect on various diseases. From several decades ago to now, cancer continues to be the leading-lethal cause worldwide. Studies have shown that natural phytochemicals derived from certain plants have the capability to prevent carcinogenesis. Therefore, new active compounds responsible for the cancer-against characteristics of dietary plants and original active compounds exert novel function on anti-carcinogenesis are important issues for cancer investigation.

Although some cancer can be cured initially, following the diagnosis of cancer, chemotherapy is used to prevent a local recurrence and spread of the primary tumor. However, the effective dose of chemotherapeutics may result in severe side effects. To reduce the suffering and enhance the survival of cancer patients, the treatment and prevention of cancer assist with natural bioactives or phytochemicals is regarded as a valid strategy in cancer therapy.

We invite the researchers to contribute original and review articles regarding the relation between phytochemicals and cancers, including the discovery of novel anti-cancer phytochemicals and the clinical application of phytochemicals on cancer treatment. Potential topics include, but are not limited to:

  • Bioactivity or toxicology of phytochemicals
  • Pharmacology or pharmaceutics of phytochemicals
  • Discovery of new natural bioactives or phytochemicals
  • New cancer therapy by phytochemicals
  • SAR studies (structure/activity relationship) of cancer preventive natural compounds
  • Natural metabolites as lead compounds for cancer prevention
  • Cancer preventive natural substances: from bench to bedside
  • The possible adverse effects or interaction between phytochemicals, such as conventional herb-neutraceutical interaction

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ecam/scps/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 698190
  • - Editorial

Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention

Shun-Fa Yang | Chia-Jui Weng | ... | Dan-Ning Hu
  • Special Issue
  • - Volume 2013
  • - Article ID 817674
  • - Research Article

Subtoxic Levels of Apigenin Inhibit Expression and Secretion of VEGF by Uveal Melanoma Cells via Suppression of ERK1/2 and PI3K/Akt Pathways

Shih-Chun Chao | Sheng-Chieh Huang | ... | Hung-Yu Lin
  • Special Issue
  • - Volume 2013
  • - Article ID 205082
  • - Research Article

Zeaxanthin Induces Apoptosis in Human Uveal Melanoma Cells through Bcl-2 Family Proteins and Intrinsic Apoptosis Pathway

Ming-Chao Bi | Richard Rosen | ... | Dan-Ning Hu
  • Special Issue
  • - Volume 2013
  • - Article ID 761852
  • - Research Article

[6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF-κB/Snail Signal Transduction Pathway

Sung Ok Kim | Mi Ryeo Kim
  • Special Issue
  • - Volume 2013
  • - Article ID 493869
  • - Research Article

In Vitro and In Vivo Anticancer Effects of Sterol Fraction from Red Algae Porphyra dentata

Katarzyna Kazłowska | Hong-Ting Victor Lin | ... | Guo-Jane Tsai
  • Special Issue
  • - Volume 2013
  • - Article ID 639083
  • - Research Article

Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

Chang Chen | Chuanhong Wu | ... | Shaojing Li
  • Special Issue
  • - Volume 2013
  • - Article ID 423164
  • - Research Article

Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways

Chi-Ming Wu | Te-Mao Li | ... | Chih-Hsin Tang
  • Special Issue
  • - Volume 2013
  • - Article ID 376123
  • - Research Article

Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERα Inhibition

Pao-Hsuan Huang | Chih-Yang Huang | ... | Ho Lin
  • Special Issue
  • - Volume 2013
  • - Article ID 468537
  • - Research Article

Ocotillol Enhanced the Antitumor Activity of Doxorubicin via p53-Dependent Apoptosis

Hongbo Wang | Pengfei Yu | ... | Fenghua Fu
  • Special Issue
  • - Volume 2013
  • - Article ID 943187
  • - Research Article

Butein Inhibits Angiogenesis of Human Endothelial Progenitor Cells via the Translation Dependent Signaling Pathway

Ching-Hu Chung | Chien-Hsin Chang | ... | Shih-Wei Wang
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate26%
Submission to final decision70 days
Acceptance to publication39 days
CiteScore2.010
Impact Factor1.984
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