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Gastroenterology Research and Practice
Volume 2012, Article ID 796751, 12 pages
Review Article

Prevention of Post-ERCP Pancreatitis

Department of Gastroenterology, Division of Medicine, Vancouver General Hospital, Vancouver, BC, Canada V5Z 1M9

Received 31 May 2011; Accepted 13 June 2011

Academic Editor: Fauze Maluf-Filho

Copyright © 2012 F. Donnellan and Michael F. Byrne. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pancreatitis is the most common complication of ERCP. It can be associated with substantial morbidity. Hence, the minimization of both the incidence and severity of post-ERCP pancreatitis is paramount. Considerable efforts have been made to identify factors that may be associated with an increased risk of this complication. In addition, both procedure- and pharmacological-related interventions have been proposed that may prevent this complication. This paper outlines these interventions and presents the evidence to support their use in the prevention of post-ERCP pancreatitis.