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Gastroenterology Research and Practice
Volume 2013, Article ID 390967, 4 pages
http://dx.doi.org/10.1155/2013/390967
Research Article

Helicobacter pylori Infection and Anemia in Taiwanese Adults

1Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung City 812, Taiwan
2Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
3School of Medicine, College of Medicine, I-Shou University and E-Da Hospital, Kaohsiung City 824, Taiwan
4Graduate Institute of Public Health, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
5Division of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
6Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
7Department of Information, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung City 801, Taiwan
8Administration Center, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
9Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
10Division of Endocrinology and Metabolism, Department of Internal Medicine, Changhua Christian Hospital, Changhua County 500, Taiwan
11Graduate Institute of Integrated Medicine, China Medical University, Taichung City 404, Taiwan
12Department of General Surgery, Changhua Christian Hospital, Changhua County 500, Taiwan
13School of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan

Received 1 August 2013; Revised 30 September 2013; Accepted 17 October 2013

Academic Editor: Chao-Hung Kuo

Copyright © 2013 Hsiang-Yao Shih et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Chronic Helicobacter pylori infection and iron-deficiency anemia (IDA) are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronic Helicobacter pylori infection and anemia remains unclear. Aim. To evaluate the association of chronic Helicobacter pylori infection and IDA. Materials and Methods. We enrolled 882 patients from January 2010 to April 2013. The status of Helicobacter pylori (H.p) infection was confirmed and blood samples from the same participants were taken on the same day to check the level of hemoglobin, serum iron, ferritin, and total iron-binding capacity (TIBC). Results. No significant difference was noted from the demographic data. The average level of hemoglobin (Hb) was not different between negative and positive groups, pos 13.57 g/dL versus neg 13.65 g/dL ( ). Although the levels of serum IDA related parameters were expected in positive group (lower serum iron and ferritin and higher TIBC) these differences did not reach statistical significance ( for iron, for ferritin, and for TIBC). Conclusion. Chronic Helicobacter pylori infection is not attributed to IDA. The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association.