Gastroenterology Research and Practice

Helicobacter pylori and Systemic Disease


Publishing date
20 Dec 2013
Status
Published
Submission deadline
02 Aug 2013

Lead Editor

1Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

2University of Malaya, Kuala Lumpur, Malaysia

3Kaohsiung Medical University, Kaohsiung 80708, Taiwan


Helicobacter pylori and Systemic Disease

Description

Helicobacter pylori (H. pylori) is a Gram-negative spiral bacterium that can cause gastritis, peptic ulcer, and gastric cancer but often remains asymptomatic. H. pylori may cause gastric mucosal damage and, at the same time, elude the immunological response evoked by the host. If H. pylori are not completely cleared, the mucosa would be infiltrated by the immunologically mediated, chronic, predominantly mononuclear cells. The chronic infection is characterized by the local production sand systemic diffusion of proinflammatory cytokines, which may exert their effects in the remote tissues and organic systems and result in extragastric manifestations.

Several studies performed during the past year supported a possible role for H. pylori infection in the pathogenesis of several extragastric diseases. Data collected from those studies clearly showed that the immunological response caused by this bacterium is not only locally oriented, but also systemically influenced the clinical course of other diseases. The interest for a possible role of H. pylori in the occurrence of some extragastric diseases seems to remain strong. H. pylori has been proven to affect ITP and IDA, while there is increasing evidence of a possible role of this bacterium in different extragastric diseases. Further studies are now needed to verify those findings.

We particularly take an interest in manuscripts that survey the relationship between H. pylori and systemic disease. Moreover, papers dealing with the effect of H. pylori on systemic disease, the tool for clinical guidance, would be of great interest (specificity, sensitivity, reproducibility, robustness, objective read-out, potential for automated analysis, characterization of H. pylori-related extragastric manifestations, and proven clinical guidance). Potential topics include, but are not limited to:

  • The relationship between H. pylori and cardiovascular diseases
  • The relationship between H. pylori and neurological diseases
  • The relationship between H. pylori and diabetes mellitus (DM)
  • The relationship between H. pylori and gynecological diseases
  • The relationship between H. pylori and ophthalmology and skin and oral mucosa diseases
  • The relationship between H. pylori and respiratory and ear, nose, and throat (E.N.T.) diseases
  • The relationship between H. pylori and hematologic diseases
  • The relationship between H. pylori and hepatobiliary diseases
  • The relationship between H. pylori and obesity, ghrelin, and leptin
  • The relationship and other Helicobacter species and systemic disease

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/grp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/grp/hpsd/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 358494
  • - Editorial

Helicobacter pylori and Systemic Disease

Chao-Hung Kuo | Yen-Hsu Chen | ... | Lin-Li Chang
  • Special Issue
  • - Volume 2013
  • - Article ID 184806
  • - Research Article

Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia

Hsi-Chang Lee | Ting-Chang Huang | ... | Deng-Chyang Wu
  • Special Issue
  • - Volume 2013
  • - Article ID 924769
  • - Research Article

Effect of Di(2-ethylhexyl)phthalate on Helicobacter pylori-Induced Apoptosis in AGS Cells

Chuang-Hao Lin | Chien-Yi Wu | ... | Fu-Chen Kuo
  • Special Issue
  • - Volume 2013
  • - Article ID 175729
  • - Clinical Study

Eradication of Helicobacter pylori Is Associated with the Progression of Dementia: A Population-Based Study

Yang-Pei Chang | Guei-Fen Chiu | ... | Fang-Jung Yu
  • Special Issue
  • - Volume 2013
  • - Article ID 390967
  • - Research Article

Helicobacter pylori Infection and Anemia in Taiwanese Adults

Hsiang-Yao Shih | Fu-Chen Kuo | ... | Yao-Li Chen
  • Special Issue
  • - Volume 2013
  • - Article ID 785892
  • - Research Article

Helicobacter pylori Infection in Dialysis Patients: A Meta-Analysis

Min Gu | Shuping Xiao | ... | Guoxin Zhang
  • Special Issue
  • - Volume 2013
  • - Article ID 932478
  • - Research Article

Ten-Day versus 14-Day Levofloxacin-Containing Triple Therapy for Second-Line Anti-Helicobacter pylori Eradication in Taiwan

Wei-Chen Tai | Chien-Hua Chiu | ... | Seng-Kee Chuah
  • Special Issue
  • - Volume 2013
  • - Article ID 570597
  • - Research Article

Risk of Atherosclerosis and Helicobacter pylori Infection according to CD14 Promotor Polymorphism in Healthy Korean Population

Sung-Goo Kang | Woo Chul Chung | ... | Kang-Moon Lee
  • Special Issue
  • - Volume 2013
  • - Article ID 436727
  • - Research Article

The Clinical Correlations of Helicobacter pylori Virulence Factors and Chronic Spontaneous Urticaria

Yi-Chun Chiu | Wei-Chen Tai | ... | Wen-Chieh Chen
Gastroenterology Research and Practice
 Journal metrics
Acceptance rate25%
Submission to final decision63 days
Acceptance to publication29 days
CiteScore3.400
Impact Factor1.806
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.