Herbal Substance, Acteoside, Alleviates Intestinal Mucositis in Mice

Figure 6

Histological sections of the jejunum stained with H&E taken at 20x magnification. Images (a) and (b) represent the PS group (control) for d 5 and d 11, respectively, with normal villi and crypts. Images (c) and (d) represent the PM group (MTX-treated) for d 5 and d 11, respectively; the administration of MTX was characterized by atrophy of the villi, increased crypt depth, and enterocyte disruption, predominantly on d 5. Images (e) and (f) represent the MA group (MTX-treated + acteoside) for d 5 and d 11, respectively; the administration of acteoside administration prevented villus and crypt damage on d 5 and d 11.

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