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Author/year | Patients | Age/sex | Cause of D-la | Comments/clinical |
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Kholostova et al./2014 [44] | 24 | <2 yrs./variable | SBS—ileojejunal rectal anastomosis for treatment of Hirschsprung’s disease | Fecal D-lactate increased in 35% pts. |
Singh et al./2013 [45] | 1 | 37/M | Antibiotic induced alteration of colonic flora causing recurrent D-la | Complicated with new acute transient systolic CHF |
Dahlquist et al./1984 [37] | 1 | 24/F | SBS—ischemic small bowel resection | Primarily CNS symptoms-lethargy, echolalia, ataxia |
Burski et al./2013 [46] | 1 | 41/F | SBS—bariatric surgery | Confusion (feeling drunk), slurred speech, ataxia. |
Gigante et al./2012 [47] | 1 | 51/F | SBS—partial small bowel resection, jejunoileal bypass due to Salmonella enteritidis infection | Confusion, blurred vision, slurred speech, nausea, weakness |
Guerrero et al./2010 [48] | 1 | 35/F | SBS—ileal resection due to ischemic bowel | Dizziness, gait instability, loss of strength |
Munakata et al./2010 [42] | 1 | 5/F | SBS—jejunoileal atresia; ileus; peritonitis probiotic use—Bifidobacterium | Intermittent ataxia, inability to grasp objects, explosive speech |
Grunert et al./2010 [49] | 1 | 7/M | Congenital disaccharidase deficiency | Found comatose after parenteral nutrition was held, and pt. had oral meals, slurred speech |
Dahhak et al./2008 [50] | 1 | 6/M | SBS—bowel surgery indication not reported | Dysarthria and disorientation |
Soler Palacín et al./2006 [51] | 1 | 11/M | SBS—multiple bowel resections in the postnatal period | Confusion, encephalopathy, slurred speech |
Puwanant et al./2005 [52] | 1 | 14/M | SBS—midgut volvulus surgery five years prior | Episodic confusion, hyperpnea |
Uchida et al./2004 [53] | 1 | 22/M | SBS—volvulus surgery at age three | Slurred speech, somnolence, gait disturbance |
Zhang et al./2003 [16] | 1 | 12/M | SBS—20 cm resection of small bowel due to volvulus | 11 episodes of weakness, ataxia, nausea, slurred speech, lethargy |
Kamar et al./2003 [54] | 1 | 80/M | SBS—subtotal colectomy with ileal J-pouch | Confusion, disorientation, tachypnea |
Azhar and Beach/2002 [55] | 1 | 53/F | SBS—colectomy and colostomy 20 years prior to Ulcerative colitis | Nausea, vomiting, fatigue, diarrhea from colostomy |
Angelet et al./2002 [56] | 1 | Unknown | SBS | Neurological symptoms |
Lalive et al./2001 [57] | 1 | 54/— | SBS—extensive small bowel surgery few months prior | Several acute confusional episodes, ataxia, nystagmus, dysarthria |
Sela et al./1999 [58] | 2 | 2.25/F 1.5/M | SBS—congenital intestinal obstruction | Encephalopathy, ataxia |
Day and Abbott/1999 [5] | 1 | Unknown | SBS | Unknown |
Vella and Farrugia/1998 [33] | 1 | 50/F | SBS | Recurrent weakness, ataxia, slurred speech, confusion, nausea |
Coronado et al./1995 [9] | 1 | 50/M | SBS—Jejunoileal bypass 2 years prior, with recent doxycycline use | Ataxia, slurred speech, weakness |
Koletzko et al./1994 [59] | 1 | 9/M | SBS—small intestinal duplication 2 years prior | Recurrent episodes—failure to thrive, unsteady gait, slurred speech, somnolence |
Gurevitch et al./1993 [60] | 1 | 1.6 yrs. | SBS—midgut volvulus | Encephalopathy syndrome |
Forsyth et al./1991 [61] | 1 | Unknown | SBS—jejunal atresia | Recurrent encephalopathy, treated with neomycin |
Flourie et al./1990 [35] | 1 | 24/M | SBS—recent treatment with Bactrim | Neurological symptoms |
Scully et al./1989 [31] | 1 | 16/M | SBS—small bowel ischemia from stab wounds | Headache, confusion, stupor, dysarthria |
Rosenthal and Pesce/1985 [62] | 1 | 2.5/M | SBS—midgut volvulus | Ataxia, lethargy |
Haan et al./1985 [63] | 1 | 8/M | SBS | Depression, slurred speech, confusion, aggressive behavior intermittently |
Traube et al./1983 [64] | 1 | 40/M | SBS—jejunoileal bypass | Bizarre behavior, slurred speech, ataxic gait |
Satoh et al./1982 [65] | 2 | Unknown | SBS | Unknown |
Schoorel et al./1980 [66] | 1 | 3/M | SBS | Confusion, dyspnea, drowsiness |
Oh et al./1979 [2] | 1 | 30/M | SBS—ischemic bowel | Slurred speech, confusion |
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