Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study
Table 2
Outcomes of esophageal ESD according to C-ESD and OTF-ESD.
C-ESD
OTF-ESD
P values
Total
Beginners
Experts
Total
Beginners
Experts
Total
Beginners
Experts
Number of lesions
16
8
8
16
8
8
Total dissection time, min
17.0 8.8
22.8 8.3
11.3 4.4
6.8 3.8
7.8 4.5
5.9 2.5
<0.001
<0.001
0.01
Lesion size, cm2
13.3 1.2
13.1 0.9
13.4 1.5
13.6 1.5
13.2 1.4
14.0 1.6
0.51
0.88
0.49
Self-completion, (%)
16 (100)
8 (100)
8 (100)
16 (100)
8 (100)
8 (100)
n.a.
n.a.
n.a.
En bloc resection, (%)
16 (100)
8 (100)
8 (100)
16 (100)
8 (100)
8 (100)
n.a.
n.a.
n.a.
Perforation, (%)
1 (6)
1 (13)
0 (0)
0 (0)
0 (0)
0 (0)
>0.99
>0.99
n.a.
Frequency of submucosal injection,
2.9 1.5
3.5 1.4
2.3 1.2
1.3 0.6
1.6 0.5
1.0 0.0
<0.001
0.005
0.02
Volume of submucosal injection, mL
15.6 7.3
18.5 7.3
13.8 6.0
5.3 2.8
6.3 3.1
4.4 2.2
<0.001
0.001
0.004
C-ESD, conventional endoscopic submucosal dissection; OTF-ESD, overtube with forceps endoscopic submucosal dissection. Continuous data are shown as the mean SD. P values were compared between the C-ESD and OTF-ESD groups.